|
|
DigiGaitTM Imaging System
We developed DigiGaitTM to image the ventral side of mice or rats as they walk on a motorized transparent treadmill belt. One high-speed camera captures the dynamics of the paws and corresponding limbs as they approach the belt during the braking phase of stance, or move away from the belt during the propulsion phase of stance just before the swing phase. The DigiGaitTM system fully quantifies the stance and swing components of stride. Proprietary software automatically calculates stride length, stride duration, stride frequency, and numerous other spatial and temporal gait indices, for each limb. This novel system was initially invented (patents pending) by Mouse Specifics to identify mice with biomarkers of gait abnormalities. We have extended the application of this unique instrument to the study of a wide array of models, pathologies, and drug-induced ataxias.
NO MORE INKING OF PAWS! NO REFLECTIVE MARKERS REQUIRED!
DigiGaitTM will become the assay of choice for phenotyping mouse models of neurodegenerative disease, arthritis, and pain, and testing the efficacy of drugs to correct motor dysfunction.
The DigiGaitTM system provides numerous spatial and temporal indices of posture and gait dynamics, including:
- Stride length
- Stance width
- Stance duration
- Swing duration
- Braking duration
- Propulsion duration
- Stride frequency
- Paw Angle
Applications include mouse models of:
- Amyotrophic lateral sclerosis
- Arthritis
- Drug-induced ataxia
- Ethanol sensitivity
- Huntington's disease
- Pain
- Parkinson's disease
- Spinal Muscular Atrophy
The method and system have now been described in several publications. Click here to see list of publications describing application of the DigiGait Imaging system.
Product Specifications
DigiGait Frequently Asked Questions
Product Inquiry
Back to the Products Page
|
