Mouse Specifics, Inc. is a leader in the development of novel phenotyping instruments for describing the effects of genes and drugs in mouse models. Our instruments enable rapid identification of gene function and drug benefit in conscious rodents. We focus on high-throughput characterization of conscious laboratory animals, yet our mission underscores refinement, replacement, and reduction of animal use in research. In 1999, we introduced e-MOUSETM, a Web-based physiological signal analyses tool and database to improve laboratory efficiencies in the collection and analyses of physiological signals. In 2000, we introduced the ECGenieTM ECG Screening System a truly high-throughput animal physiology screen, for recording electrocardiograms in conscious mice without the need for restraint, anesthesia, or surgery. In 2004, we extended this technology to include electrocardiograms in conscious rats and guinea pigs, with introduction of The ECGenieTM. With the ECGenieTM and e-MOUSETM ECG analyses, one investigator can non-invasively screen large quantities of laboratory animals with one instrument for the presence of arrhythmia, cardiovascular phenotypes, and drug cardiotoxicity.

Ingenéous!TM Discovery Tools: Better Means of Expression.
Designed by physiologists and biomedical engineers, MSI's Ingenéous!TM Discovery Tools are instruments for rapidly identifying relevant phenotypes in mouse models. We have developed novel sensor and imaging technologies to non-invasively monitor cardiac function and motor activity in conscious mice without the need for anesthetic or surgery. These instruments provide excellent data in unadulterated animals - the same animals can be used for other studies, thereby reducing the overall quantity required. Is cardiac function altered? Do your mice have an altered gait? Does your drug cause arrhythmias or ataxia? Our products and services will help you to readily answer these questions.

Thomas G. Hampton, PhD - CEO
Dr. Hampton is the founder of Mouse Specifics, Inc. A biomedical engineer and physiologist, he has assembled a team committed to developing novel instruments specific to the study of murine physiology. Dr. Hampton has coauthored numerous published studies involving animal physiology. The MSI Scientific Advisory Board ensures that our efforts are consistent with our Mission. Dr. Hampton is joined by a staff of engineers and physiologists who share his vision of better data from every mouse.

Ajit Kale - Technology & Software Development
Mr. Kale joined MSI in 2001. He holds a BS in Physics and an MS in Software Technology and has 8 years of experience in developing software for information technology. He worked for 3 years in a lead role for developing non-invasive techniques in medical research, based on image and signal processing. Mr. Kale completed a research fellowship for advanced techniques in image and signal processing for optical microscopy by the United Nations at ICS - Trieste (Italy) by the United Nations Industrial development Organization. He has also authored several published papers and web publications. Ajit is an expert in analysis, design, programming, testing, integration and implementation of complex research and business applications.
ajit_kale@mousespecifics.com

Chuck Brown - Business Development / Finance
Mr. Brown joined Mouse Specifics in 2002. He has 9 years of experience in the health care and life science industries, working mostly in financial and strategic advisory roles. Mr. Brown was a health care corporate finance professional for CIBC World Markets, advising senior management teams in mergers and acquisitions and in raising equity and debt capital. Prior to his experience in corporate finance, Mr. Brown was a business development manager in the healthcare technology division of Harris Corporation (NYSE: HRS), serving the pathology, radiology, and medical records markets. He holds an MBA in finance from the Darden Graduate School of Business at the University of Virginia and a BA from the University of North Carolina.
chuckbrown@mousespecifics.com

Scott McCue - Sales
Mr. McCue joined Mouse Specifics in 2003, and is responsible for driving the company's sales efforts. He brings a wealth of knowledge and experience in technical equipment sales to MSI. Prior to MSI, Mr. McCue was a sales engineer for a manufacturer/ distributor specializing in non-destructive testing. He holds a B.S. in Mechanical Engineering from Villanova University.
smccue@mousespecifics.com